Prevention of Ventricular Arrhythmia and Calcium Dysregulation in a Catecholaminergic Polymorphic Ventricular Tachycardia Mouse Model Carrying Calsequestrin-2 Mutation

BACKGROUND: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a familial arrhythmic syndrome caused by mutations in genes encoding the calcium-regulation proteins cardiac ryanodine receptor (RyR2) or calsequestrin-2 (CASQ2). Mechanistic studies indicate that CPVT is mediated by diastol...

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Detalhes bibliográficos
Main Authors: Alcalai, Ronny, Wakimoto, Hiroko, Arad, Michael, Planer, David, Konno, Tetsuo, Wang, Libin, Seidman, Jon G., Seidman, Christine E., Berul, Charles I
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053436/
https://ncbi.nlm.nih.gov/pubmed/20807279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1540-8167.2010.01877.x
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