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Short Telomeres Compromise β-Cell Signaling and Survival

The genetic factors that underlie the increasing incidence of diabetes with age are poorly understood. We examined whether telomere length, which is inherited and known to shorten with age, plays a role in the age-dependent increased incidence of diabetes. We show that in mice with short telomeres,...

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Detalhes bibliográficos
Main Authors: Guo, Nini, Parry, Erin M., Li, Luo-Sheng, Kembou, Frant, Lauder, Naudia, Hussain, Mehboob A., Berggren, Per-Olof, Armanios, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053388/
https://ncbi.nlm.nih.gov/pubmed/21423765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017858
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