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Short Telomeres Compromise β-Cell Signaling and Survival

The genetic factors that underlie the increasing incidence of diabetes with age are poorly understood. We examined whether telomere length, which is inherited and known to shorten with age, plays a role in the age-dependent increased incidence of diabetes. We show that in mice with short telomeres,...

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Bibliografske podrobnosti
Main Authors: Guo, Nini, Parry, Erin M., Li, Luo-Sheng, Kembou, Frant, Lauder, Naudia, Hussain, Mehboob A., Berggren, Per-Olof, Armanios, Mary
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053388/
https://ncbi.nlm.nih.gov/pubmed/21423765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017858
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