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Sigma Receptor 1 Modulates Endoplasmic Reticulum Stress in Retinal Neurons
PURPOSE. To investigate the mechanism of σ receptor 1 (σR1) neuroprotection in retinal neurons. METHODS. Oxidative stress, which is implicated in diabetic retinopathy, was induced in mouse primary ganglion cells (GCs) and RGC-5 cells, and the effect of the σR1 ligand (+)-pentazocine on pro- and anti...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Association for Research in Vision and Ophthalmology, Inc.
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3053296/ https://ncbi.nlm.nih.gov/pubmed/20811050 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.10-5731 |
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