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Cerebral cavernous malformation gene CCM3 is critical for vascular development by regulating VEGFR2 signaling
Cerebral cavernous malformations (CCMs) are human vascular malformations caused by mutations in three genes of unknown function: CCM1, CCM2, and CCM3. CCM3, also known as PDCD10 (programmed cell death 10), was initially identified by its mRNA induction by apoptotic stimuli in vitro. However, the in...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3052863/ https://ncbi.nlm.nih.gov/pubmed/20371769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2000722 |
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