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Ccm3, a gene associated with cerebral cavernous malformations, is required for neuronal migration
Loss of function of cerebral cavernous malformation 3 (CCM3) results in an autosomal dominant cerebrovascular disorder. Here, we uncover a developmental role for CCM3 in regulating neuronal migration in the neocortex. Using cell type-specific gene inactivation in mice, we show that CCM3 has both cel...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Company of Biologists
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943187/ https://ncbi.nlm.nih.gov/pubmed/24595293 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.093526 |
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