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High-throughput screening of microscale pitted substrate topographies for enhanced nonviral transfection efficiency in primary human fibroblasts

Optimization of nonviral gene delivery typically focuses on the design of particulate carriers that are endowed with desirable membrane targeting, internalization, and endosomal escape properties. Topographical control of cell transfectability, however, remains a largely unexplored parameter. Emergi...

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Detalhes bibliográficos
Main Authors: Adler, Andrew F., Speidel, Alessondra T., Christoforou, Nicolas, Kolind, Kristian, Foss, Morten, Leong, Kam W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052739/
https://ncbi.nlm.nih.gov/pubmed/21334062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.01.040
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