Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture

Mutations that occurred during adaptation of human cytomegalovirus to cell culture were monitored by isolating four strains from clinical samples, passaging them in various cell types and sequencing ten complete virus genomes from the final passages. Mutational dynamics were assessed by targeted seq...

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Detalhes bibliográficos
Main Authors: Dargan, Derrick J., Douglas, Elaine, Cunningham, Charles, Jamieson, Fiona, Stanton, Richard J., Baluchova, Katarina, McSharry, Brian P., Tomasec, Peter, Emery, Vincent C., Percivalle, Elena, Sarasini, Antonella, Gerna, Giuseppe, Wilkinson, Gavin W. G., Davison, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for General Microbiology 2010
Assuntos:
Animal
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052722/
https://ncbi.nlm.nih.gov/pubmed/20479471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.018994-0
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