Sequential mutations associated with adaptation of human cytomegalovirus to growth in cell culture

Mutations that occurred during adaptation of human cytomegalovirus to cell culture were monitored by isolating four strains from clinical samples, passaging them in various cell types and sequencing ten complete virus genomes from the final passages. Mutational dynamics were assessed by targeted seq...

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Bibliografiska uppgifter
Huvudupphovsmän: Dargan, Derrick J., Douglas, Elaine, Cunningham, Charles, Jamieson, Fiona, Stanton, Richard J., Baluchova, Katarina, McSharry, Brian P., Tomasec, Peter, Emery, Vincent C., Percivalle, Elena, Sarasini, Antonella, Gerna, Giuseppe, Wilkinson, Gavin W. G., Davison, Andrew J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for General Microbiology 2010
Ämnen:
Animal
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052722/
https://ncbi.nlm.nih.gov/pubmed/20479471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.018994-0
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