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Impact of Sequence Variation in the UL128 Locus on Production of Human Cytomegalovirus in Fibroblast and Epithelial Cells

The human cytomegalovirus (HCMV) virion envelope contains a complex consisting of glycoproteins gH and gL plus proteins encoded by the UL128 locus (UL128L): pUL128, pUL130, and pUL131A. UL128L is necessary for efficient infection of myeloid, epithelial, and endothelial cells but limits replication i...

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Detalhes bibliográficos
Main Authors: Murrell, Isa, Tomasec, Peter, Wilkie, Gavin S., Dargan, Derrick J., Davison, Andrew J., Stanton, Richard J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3807394/
https://ncbi.nlm.nih.gov/pubmed/23885075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01546-13
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