Reduced gain of excitation contraction coupling in triadin-null myotubes is mediated by the disruption of FKBP12/RyR1 interaction

Several studies have suggested that triadin (Tdn) may be a critical component of skeletal EC-coupling. However, using Tdn-null mice we have shown that triadin ablation results in no significant disruption of skeletal EC-coupling. To analyze the role of triadin in EC-coupling signaling here we used w...

Full description

Saved in:
Bibliographic Details
Main Authors: Eltit, Jose M., Szpyt, John, Li, Hongli, Allen, Paul D., Perez, Claudio F.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052628/
https://ncbi.nlm.nih.gov/pubmed/21310482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2011.01.005
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items