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Calcitonin gene-related peptide restores disrupted excitation–contraction coupling in myotubes expressing central core disease mutations in RyR1
ABSTRACT: Central core disease (CCD) is a congenital human myopathy associated with mutations in the gene encoding the skeletal muscle ryanodine receptor (RyR1), resulting in skeletal muscle weakness and lower limb deformities. The muscle weakness can be at least partially explained by a reduced mag...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Blackwell Science Inc
2011
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3213414/ https://ncbi.nlm.nih.gov/pubmed/21825032 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.210765 |
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