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The role of DYRK1A in neurodegenerative diseases

Recent studies indicate that the dual-specificity tyrosine phosphorylated-regulated kinase 1A (DYRK1A) gene, which is located on chromosome 21q22.2 and is overexpressed in Down syndrome (DS), may play a significant role in developmental brain defects and in early-onset neurodegeneration, neuronal lo...

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Bibliografische gegevens
Hoofdauteurs: Wegiel, Jerzy, Gong, Cheng-Xin, Hwang, Yu-Wen
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052627/
https://ncbi.nlm.nih.gov/pubmed/21156028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1742-4658.2010.07955.x
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