Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus

The ‘classical’ swine H1N1 influenza A virus lineage was established after the devastating 1918 human pandemic virus entered domestic pig herds. A descendent of this lineage recently re-emerged in humans as the 2009 pandemic H1N1 virus. Adaptation in pigs has led to several changes in the multifunct...

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Bibliografiska uppgifter
Huvudupphovsmän: Hale, Benjamin G., Steel, John, Manicassamy, Balaji, Medina, Rafael A., Ye, Jianqiang, Hickman, Danielle, Lowen, Anice C., Perez, Daniel R., García-Sastre, Adolfo
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for General Microbiology 2010
Ämnen:
Animal
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052525/
https://ncbi.nlm.nih.gov/pubmed/20237225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/vir.0.020925-0
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