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A new influenza virus virulence determinant: The NS1 protein four C-terminal residues modulate pathogenicity

The virulence of influenza virus is a multigenic trait. One determinant of virulence is the multifunctional NS1 protein that functions in several ways to defeat the cellular innate immune response. Recent large-scale genome sequence analysis of avian influenza virus isolates indicated that four C-te...

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Detalhes bibliográficos
Main Authors: Jackson, David, Hossain, Md. Jaber, Hickman, Danielle, Perez, Daniel R., Lamb, Robert A.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393797/
https://ncbi.nlm.nih.gov/pubmed/18334632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800482105
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