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Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs
MicroRNAs (miRNAs) are initially expressed as long transcripts that are processed in the nucleus to yield ∼65-nucleotide (nt) RNA hairpin intermediates, termed pre-miRNAs, that are exported to the cytoplasm for additional processing to yield mature, ∼22-nt miRNAs. Here, we demonstrate that human pre...
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| Autors principals: | , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Cold Spring Harbor Laboratory Press
2003
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC305252/ https://ncbi.nlm.nih.gov/pubmed/14681208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1158803 |
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