Exportin-5 mediates the nuclear export of pre-microRNAs and short hairpin RNAs

MicroRNAs (miRNAs) are initially expressed as long transcripts that are processed in the nucleus to yield ∼65-nucleotide (nt) RNA hairpin intermediates, termed pre-miRNAs, that are exported to the cytoplasm for additional processing to yield mature, ∼22-nt miRNAs. Here, we demonstrate that human pre...

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Bibliographic Details
Main Authors: Yi, Rui, Qin, Yi, Macara, Ian G., Cullen, Bryan R.
Format: Artigo
Language:Inglês
Published: Cold Spring Harbor Laboratory Press 2003
Subjects:
Research Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC305252/
https://ncbi.nlm.nih.gov/pubmed/14681208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1158803
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