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Phencyclidine is a negative allosteric modulator of signal transduction at two subclasses of excitatory amino acid receptors.
Phencyclidine (PCP) and some of its pharmacological congeners inhibit the signal transduction at specific excitatory amino acid receptors of cerebellar granule cells in primary cultures. These drugs do not bind to the transmitter recognition sites, and affinity of this specific binding site is incre...
Enregistré dans:
| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
1987
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305248/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3037532/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.5068 |
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