High-frequency deletional rearrangement of immunoglobulin kappa gene segments introduced into a pre-B-cell line.
We describe an immunoglobulin gene recombination indicator in which a specific rearrangement via deletion results in the acquisition of a dominant phenotype. The indicator consists of the Escherichia coli xanthine/guanine phosphoribosyltransferase (gpt) gene, whose translation is prevented by the pr...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
1987
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110776/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.4949 |
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