High-frequency deletional rearrangement of immunoglobulin kappa gene segments introduced into a pre-B-cell line.

We describe an immunoglobulin gene recombination indicator in which a specific rearrangement via deletion results in the acquisition of a dominant phenotype. The indicator consists of the Escherichia coli xanthine/guanine phosphoribosyltransferase (gpt) gene, whose translation is prevented by the pr...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Engler, P, Storb, U
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1987
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305224/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3110776/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.14.4949
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