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Analyses of gating thermodynamics and effects of deletions in the mechanosensitive channel TREK-1: Comparisons with structural models

TREK-1, a mechanosensitive K channel from the two-pore family (K(2)P), is involved in protective regulation of the resting potential in CNS neurons and other tissues. The structure of TREK-1 and the basis of its sensitivity to stretch and variety of lipid-soluble factors remain unknown. Using existi...

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Detalhes bibliográficos
Main Authors: Maksaev, Grigory, Milac, Adina, Anishkin, Andriy, Guy, H Robert, Sukharev, Sergei
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052206/
https://ncbi.nlm.nih.gov/pubmed/21057213
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.1.13906
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