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Structural models of TREK channels and their gating mechanism

Mechanosensitive TREK channels belong to the family of K2P channels, a family of widely distributed, well-modulated channels that uniquely have two similar or identical subunits, each with two TM1-P-TM2 motifs. Our goal is to build viable structural models of TREK channels, as representatives of K2P...

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Autors principals: Milac, Adina L, Anishkin, Andriy, Fatakia, Sarosh N, Chow, Carson C, Sukharev, Sergei, Guy, H Robert
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3052205/
https://ncbi.nlm.nih.gov/pubmed/21084863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/chan.5.1.13905
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