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State-stabilizing Interactions in Bacterial Mechanosensitive Channel Gating and Adaptation

We outline several principles that we believe define the gating of two bacterial mechanosensitive channels, MscL and MscS. Serving as turgor regulators in bacteria and other walled cells, these molecules are tangible models for studying conformational transitions in membrane proteins driven directly...

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Hlavní autoři: Anishkin, Andriy, Sukharev, Sergei
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740535/
https://ncbi.nlm.nih.gov/pubmed/19383606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.009357
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