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State-stabilizing Interactions in Bacterial Mechanosensitive Channel Gating and Adaptation

We outline several principles that we believe define the gating of two bacterial mechanosensitive channels, MscL and MscS. Serving as turgor regulators in bacteria and other walled cells, these molecules are tangible models for studying conformational transitions in membrane proteins driven directly...

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Autors principals: Anishkin, Andriy, Sukharev, Sergei
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2740535/
https://ncbi.nlm.nih.gov/pubmed/19383606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R109.009357
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