Lipoamide or lipoic acid stimulates mitochondrial biogenesis in 3T3-L1 adipocytes via the endothelial NO synthase-cGMP-protein kinase G signalling pathway

BACKGROUND AND PURPOSE: Metabolic dysfunction due to loss of mitochondria plays an important role in diabetes, and stimulation of mitochondrial biogenesis by anti-diabetic drugs improves mitochondrial function. In a search for potent stimulators of mitochondrial biogenesis, we examined the effects a...

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Main Authors: Shen, Weili, Hao, Jiejie, Feng, Zhihui, Tian, Chuan, Chen, Weijun, Packer, Lester, Shi, Xianglin, Zang, Weijin, Liu, Jiankang
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Science Inc 2011
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Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051392/
https://ncbi.nlm.nih.gov/pubmed/21108628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.01134.x
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