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2′,3′-cGMP exists in vivo and comprises a 2′,3′-cGMP-guanosine pathway

The discovery in 2009 that 2′,3′-cAMP exists in biological systems was rapidly followed by identification of 2′,3′-cGMP in cell and tissue extracts. To determine whether 2′,3′-cGMP exists in mammals under physiological conditions, we used ultraperformance LC-MS/MS to measure 2′,3′-cAMP and 2′,3′-cGM...

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Detalhes bibliográficos
Publicado no:Am J Physiol Regul Integr Comp Physiol
Main Authors: Jackson, Edwin K., Mi, Zaichuan, Janesko-Feldman, Keri, Jackson, Travis C., Kochanek, Patrick M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620655/
https://ncbi.nlm.nih.gov/pubmed/30789788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpregu.00401.2018
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