Caffeic acid phenethyl ester decreases cholangiocarcinoma growth by inhibition of NF-κB and induction of apoptosis

Caffeic acid phenethyl ester (CAPE) inhibits the growth of tumor cells and is a known inhibitor of NF-κB that is constitutively active in cholangiocarcinoma (CCH) cells. We evaluated the effects of CAPE on CCH growth both in vitro and in vivo. Inhibition of NF-κB DNA-binding activity was confirmed i...

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Detalhes bibliográficos
Main Authors: Onori, Paolo, DeMorrow, Sharon, Gaudio, Eugenio, Franchitto, Antonio, Mancinelli, Romina, Venter, Julie, Kopriva, Shelley, Ueno, Yoshiyuki, Alvaro, Domenico, Savage, Jennifer, Alpini, Gianfranco, Francis, Heather
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051346/
https://ncbi.nlm.nih.gov/pubmed/19358267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.24271
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