The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway

Cholangiocarcinomas are cancers that have poor prognosis and limited treatment options. The noncanonical Wnt pathway is mediated predominantly by Wnt 5a, which activates a Ca(2+)-dependent pathway involving protein kinase C, or a Ca(2+)-independent pathway involving the orphan receptor Ror2 and subs...

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Detaylı Bibliyografya
Asıl Yazarlar: DeMorrow, Sharon, Francis, Heather, Gaudio, Eugenio, Venter, Julie, Franchitto, Antonio, Kopriva, Shelley, Onori, Paolo, Mancinelli, Romina, Frampton, Gabriel, Coufal, Monique, Mitchell, Brett, Vaculin, Bradley, Alpini, Gianfranco
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Physiological Society 2008
Konular:
Liver and Biliary Tract
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604798/
https://ncbi.nlm.nih.gov/pubmed/18832445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90455.2008
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