The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway

Cholangiocarcinomas are cancers that have poor prognosis and limited treatment options. The noncanonical Wnt pathway is mediated predominantly by Wnt 5a, which activates a Ca(2+)-dependent pathway involving protein kinase C, or a Ca(2+)-independent pathway involving the orphan receptor Ror2 and subs...

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Bibliografiske detaljer
Main Authors: DeMorrow, Sharon, Francis, Heather, Gaudio, Eugenio, Venter, Julie, Franchitto, Antonio, Kopriva, Shelley, Onori, Paolo, Mancinelli, Romina, Frampton, Gabriel, Coufal, Monique, Mitchell, Brett, Vaculin, Bradley, Alpini, Gianfranco
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2008
Fag:
Liver and Biliary Tract
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604798/
https://ncbi.nlm.nih.gov/pubmed/18832445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90455.2008
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