The endocannabinoid anandamide inhibits cholangiocarcinoma growth via activation of the noncanonical Wnt signaling pathway

Cholangiocarcinomas are cancers that have poor prognosis and limited treatment options. The noncanonical Wnt pathway is mediated predominantly by Wnt 5a, which activates a Ca(2+)-dependent pathway involving protein kinase C, or a Ca(2+)-independent pathway involving the orphan receptor Ror2 and subs...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: DeMorrow, Sharon, Francis, Heather, Gaudio, Eugenio, Venter, Julie, Franchitto, Antonio, Kopriva, Shelley, Onori, Paolo, Mancinelli, Romina, Frampton, Gabriel, Coufal, Monique, Mitchell, Brett, Vaculin, Bradley, Alpini, Gianfranco
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Physiological Society 2008
Θέματα:
Liver and Biliary Tract
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2604798/
https://ncbi.nlm.nih.gov/pubmed/18832445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90455.2008
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