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A cryptic sensor for HIV-1 activates antiviral innate immunity in dendritic cells

Dendritic cells (DC) serve a key function in host defense, linking innate detection of microbes to the activation of pathogen-specific adaptive immune responses(1,2). Whether there is cell-intrinsic recognition of HIV-1 by host innate pattern-recognition receptors and subsequent coupling to antivira...

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Detalhes bibliográficos
Main Authors: Manel, Nicolas, Hogstad, Brandon, Wang, Yaming, Levy, David E., Unutmaz, Derya, Littman, Dan R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051279/
https://ncbi.nlm.nih.gov/pubmed/20829794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature09337
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