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Censoring the sensors: how HIV flies under the radar of innate immunity
Two groups have identified SAMHD1, a protein encoded by an Aicardi-Goutières Syndrome susceptibility gene, as the factor that restricts infection of macrophages and dendritic cells with HIV-1. Here we discuss implications of this discovery for induction of antiviral protective immunity.
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3624893/ https://ncbi.nlm.nih.gov/pubmed/22000008 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.09.010 |
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