Oxidative stress induces protein and DNA radical formation in follicular dendritic cells (FDCs) of the germinal center and modulates its cell death patterns in late sepsis

Profound depletion of follicular dendritic cells (FDCs) is a hallmark of sepsis-like syndrome, but the exact causes for the ensuing cell death are unknown. The cell death-driven depletion contributes to immunoparalysis and is responsible for most of the morbidity and mortality in sepsis. Here we hav...

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Bibliografiset tiedot
Päätekijät: Chatterjee, Saurabh, Lardinois, Olivier, Bhattacharjee, Suchandra, Tucker, Jeff, Corbett, Jean, Deterding, Leesa, Ehrenshaft, Marilyn, Bonini, Marcelo, Mason, Ronald P.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3051032/
https://ncbi.nlm.nih.gov/pubmed/21215311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.12.037
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