Stimulation of the Glucocorticoid-Induced TNF Receptor Family-Related Receptor on CD8 T Cells Induces Protective and High-Avidity T Cell Responses to Tumor-Specific Antigens

Treatment of tumor-bearing mice with a stimulatory Ab to glucocorticoid-induced TNFR family-related receptor (GITR) has previously been shown to elicit protective T cell responses against poorly immunogenic tumors. However, the role of GITR stimulation on CD8 T cells and the nature of tumor rejectio...

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Hlavní autoři: Côté, Anik L., Zhang, Peisheng, O’Sullivan, Jeremy A., Jacobs, Valerie L., Clemis, Carli R., Sakaguchi, Shimon, Guevara-Patiño, José A., Turk, Mary Jo
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050990/
https://ncbi.nlm.nih.gov/pubmed/21106849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001308
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