Identification of residues required for ligand binding to the beta-adrenergic receptor.

The functional significance of conserved polar amino acids within the putative transmembrane region of the beta-adrenergic receptor (beta AR) was examined by oligonucleotide-directed mutagenesis of the hamster gene encoding beta AR and expression of the mutant genes in COS-7 cells. Although a substi...

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Autores principales: Strader, C D, Sigal, I S, Register, R B, Candelore, M R, Rands, E, Dixon, R A
Formato: Artigo
Lenguaje:Inglês
Publicado: 1987
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC305093/
https://ncbi.nlm.nih.gov/pubmed/2885836
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