Identification of residues required for ligand binding to the beta-adrenergic receptor.

The functional significance of conserved polar amino acids within the putative transmembrane region of the beta-adrenergic receptor (beta AR) was examined by oligonucleotide-directed mutagenesis of the hamster gene encoding beta AR and expression of the mutant genes in COS-7 cells. Although a substi...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Strader, C D, Sigal, I S, Register, R B, Candelore, M R, Rands, E, Dixon, R A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1987
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305093/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2885836/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.13.4384
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