Anesthetic Propofol Reduces Endotoxic Inflammation by Inhibiting Reactive Oxygen Species-regulated Akt/IKKβ/NF-κB Signaling

BACKGROUND: Anesthetic propofol has immunomodulatory effects, particularly in the area of anti-inflammation. Bacterial endotoxin lipopolysaccharide (LPS) induces inflammation through toll-like receptor (TLR) 4 signaling. We investigated the molecular actions of propofol against LPS/TLR4-induced infl...

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Detalhes bibliográficos
Main Authors: Hsing, Chung-Hsi, Lin, Ming-Chung, Choi, Pui-Ching, Huang, Wei-Ching, Kai, Jui-In, Tsai, Cheng-Chieh, Cheng, Yi-Lin, Hsieh, Chia-Yuan, Wang, Chi-Yun, Chang, Yu-Ping, Chen, Yu-Hong, Chen, Chia-Ling, Lin, Chiou-Feng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050912/
https://ncbi.nlm.nih.gov/pubmed/21408125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0017598
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