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Propofol Treatment Inhibits Constitutive Apoptosis in Human Primary Neutrophils and Granulocyte-Differentiated Human HL60 Cells

Apoptosis regulation is essential for neutrophil homeostasis. We previously demonstrated that a process involving glycogen synthase kinase (GSK)-3β determines neutrophil apoptosis. As for this apoptotic process, an overdose of propofol (2,6-Diisopropylphenol; 25 μg/ml or 140 μM) also causes GSK-3β-m...

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Pubblicato in:PLoS One
Autori principali: Hsing, Chung-Hsi, Chen, Chia-Ling, Lin, Wei-Chieh, Lin, Chiou-Feng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4465642/
https://ncbi.nlm.nih.gov/pubmed/26061531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0129693
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