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Anesthetic Propofol Overdose Causes Vascular Hyperpermeability by Reducing Endothelial Glycocalyx and ATP Production

Prolonged treatment with a large dose of propofol may cause diffuse cellular cytotoxicity; however, the detailed underlying mechanism remains unclear, particularly in vascular endothelial cells. Previous studies showed that a propofol overdose induces endothelial injury and vascular barrier dysfunct...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Lin, Ming-Chung, Lin, Chiou-Feng, Li, Chien-Feng, Sun, Ding-Ping, Wang, Li-Yun, Hsing, Chung-Hsi
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4490431/
https://ncbi.nlm.nih.gov/pubmed/26023717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160612092
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