Cooperation between Stat3 and Akt Signaling Leads to Prostate Tumor Development in Transgenic Mice

In this report, we describe the development of a transgenic mouse in which a rat probasin promoter (ARR(2)Pb) was used to direct prostate specific expression of a constitutively active form of signal transducer and activator of transcription 3 (i.e., Stat3C). ARR(2)Pb.Stat3C mice exhibited hyperplas...

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Bibliografiske detaljer
Main Authors: Blando, Jorge M, Carbajal, Steve, Abel, Erika, Beltran, Linda, Conti, Claudio, Fischer, Susan, DiGiovanni, John
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050868/
https://ncbi.nlm.nih.gov/pubmed/21390188
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