Irinotecan Synergistically Enhances the Antiproliferative and Proapoptotic Effects of Axitinib In Vitro and Improves Its Anticancer Activity In Vivo

AIMS: To demonstrate the synergistic antiproliferative and proapoptotic activity of irinotecan and axitinib in vitro and the improvement of the in vivo effects on angiogenesis and pancreatic cancer. METHODS: Proliferation and apoptotic assays were performed on human dermal microvascular endothelial...

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Bibliografiske detaljer
Main Authors: Canu, Bastianina, Fioravanti, Anna, Orlandi, Paola, Di Desidero, Teresa, Alì, Greta, Fontanini, Gabriella, Di Paolo, Antonello, Del Tacca, Mario, Danesi, Romano, Bocci, Guido
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050865/
https://ncbi.nlm.nih.gov/pubmed/21390185
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