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Simultaneous, But Not Consecutive, Combination With Folinate Salts Potentiates 5-Fluorouracil Antitumor Activity In Vitro and In Vivo

The combination of folinate salts to 5-fluoruracil (5-FU)-based schedules is an established clinical routine in the landscape of colorectal cancer treatment. The aim of this study was to investigate the pharmacological differences between the sequential administration of folinate salts (1 h before,...

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Détails bibliographiques
Publié dans:Oncol Res
Auteurs principaux: Di Paolo, Antonello, Orlandi, Paola, Di Desidero, Teresa, Danesi, Romano, Bocci, Guido
Format: Artigo
Langue:Inglês
Publié: Cognizant Communication Corporation 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7841196/
https://ncbi.nlm.nih.gov/pubmed/28109077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3727/096504017X14841698396900
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