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Predicting the points of interaction of small molecules in the NF-κB pathway

BACKGROUND: The similarity property principle has been used extensively in drug discovery to identify small compounds that interact with specific drug targets. Here we show it can be applied to identify the interactions of small molecules within the NF-κB signalling pathway. RESULTS: Clusters that c...

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Bibliografski detalji
Glavni autori: Patel, Yogendra, Heyward, Catherine A, White, Michael RH, Kell, Douglas B
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050742/
https://ncbi.nlm.nih.gov/pubmed/21342508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-5-32
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