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Bindarit: An anti-inflammatory small molecule that modulates the NFκB pathway

The activation of nuclear factor (NF)κB pathway and its transducing signaling cascade has been associated with the pathogenesis of many inflammatory diseases. The central role that IκBα and p65 phosphorylation play in regulating NFκB signalling in response to inflammatory stimuli made these proteins...

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Bibliografiske detaljer
Main Authors: Mora, Eugenio, Guglielmotti, Angelo, Biondi, Giuseppe, Sassone-Corsi, Paolo
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356824/
https://ncbi.nlm.nih.gov/pubmed/22189654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.1.18559
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