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Bindarit: An anti-inflammatory small molecule that modulates the NFκB pathway

The activation of nuclear factor (NF)κB pathway and its transducing signaling cascade has been associated with the pathogenesis of many inflammatory diseases. The central role that IκBα and p65 phosphorylation play in regulating NFκB signalling in response to inflammatory stimuli made these proteins...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mora, Eugenio, Guglielmotti, Angelo, Biondi, Giuseppe, Sassone-Corsi, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356824/
https://ncbi.nlm.nih.gov/pubmed/22189654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.1.18559
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