Arginine decarboxylase inhibitors reduce the capacity of Trypanosoma cruzi to infect and multiply in mammalian host cells.

The capacity of blood (trypomastigote) forms of Trypanosoma cruzi to infect mouse peritoneal macrophages or rat heart myoblasts in vitro was inhibited by treatment of the trypomastigotes with DL-alpha-difluoromethylarginine (F2Me Arg), monofluoromethylagmatine, or (E)-alpha-monofluoromethyl-3-4-dehy...

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Cyhoeddwyd yn:	Proc Natl Acad Sci U S A
Prif Awduron:	Kierszenbaum, F, Wirth, J J, McCann, P P, Sjoerdsma, A
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	National Academy of Sciences 1987
Pynciau:	Research Article
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC305068/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3295879/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.12.4278
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