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A pairwise chemical genetic screen identifies new inhibitors of glucose transport

Oxidative phosphorylation (OXPHOS) and glycolysis are the two main pathways that control energy metabolism of a cell. The Warburg effect, in which glycolysis remains active even under aerobic conditions, is considered a key driver for cancer cell proliferation, malignancy, metastasis and therapeutic...

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Hlavní autoři: Ulanovskaya, Olesya A., Cui, Jiayue, Kron, Stephen J., Kozmin, Sergey A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050591/
https://ncbi.nlm.nih.gov/pubmed/21338919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.12.015
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