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HIV-1 Tat induced-platelet activation and release of CD154 contribute to HIV-1 associated autoimmune thrombocytopenia

BACKGROUND: Enhanced platelet activation in HIV-1 infected patients has been reported and shown to strongly correlate with plasma viral load. Activated platelets are known to express and to release a variety of proteins that can modulate the immune system. Specifically, platelet derived CD154 has sh...

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Detalhes bibliográficos
Main Authors: Wang, Jianhui, Zhang, Wei, Nardi, Michael A., Li, Zongdong
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050111/
https://ncbi.nlm.nih.gov/pubmed/21143381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2010.04168.x
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