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Role of molecular mimicry to HIV-1 peptides in HIV-1–related immunologic thrombocytopenia
Patients with early HIV-1 infection develop an autoimmune thrombocytopenia in which antibody is directed against an immunodominant epitope of the β(3) (glycoprotein IIIa [GPIIIa]) integrin, GPIIIa49-66. This antibody induces thrombocytopenia by a novel complement-independent mechanism in which plate...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The American Society of Hematology
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1895171/ https://ncbi.nlm.nih.gov/pubmed/15774614 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0243 |
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