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Role of molecular mimicry to HIV-1 peptides in HIV-1–related immunologic thrombocytopenia

Patients with early HIV-1 infection develop an autoimmune thrombocytopenia in which antibody is directed against an immunodominant epitope of the β(3) (glycoprotein IIIa [GPIIIa]) integrin, GPIIIa49-66. This antibody induces thrombocytopenia by a novel complement-independent mechanism in which plate...

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Bibliografiske detaljer
Main Authors: Li, Zongdong, Nardi, Michael A., Karpatkin, Simon
Format: Artigo
Sprog:Inglês
Udgivet: The American Society of Hematology 2005
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895171/
https://ncbi.nlm.nih.gov/pubmed/15774614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-01-0243
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