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Platelet-derived or soluble CD154 induces vascularized allograft rejection independent of cell-bound CD154
CD154 is a cell surface molecule expressed on activated T cells that binds to CD40, an activating molecule on APCs. Its blockade has been shown to prevent allograft rejection, presumably by interrupting interactions between T cells and APCs. It is known that activated human platelets express and she...
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| Autores principales: | , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1378189/ https://ncbi.nlm.nih.gov/pubmed/16498500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27155 |
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