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De Novo Design of Helical Bundles as Models for Understanding Protein Folding and Function

De novo protein design has proven to be a powerful tool for understanding protein folding, structure, and function. In this Account, we highlight aspects of our research on the design of dimeric, four-helix bundles. Dimeric, four-helix bundles are found throughout nature, and the history of their de...

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Autors principals: HILL, R. BLAKE, RALEIGH, DANIEL P., LOMBARDI, ANGELA, DEGRADO, WILLIAM F.
Format: Artigo
Idioma:Inglês
Publicat: 2000
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3050006/
https://ncbi.nlm.nih.gov/pubmed/11087311
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