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Obesity impairs skeletal muscle AMPK signaling during exercise: role of AMPKα2 in the regulation of exercise capacity in vivo

OBJECTIVE: Skeletal muscle AMP-activated protein kinase (AMPK)α2 activity is impaired in obese, insulin resistant individuals during exercise. We determined whether this defect contributes to the metabolic dysregulation and reduced exercise capacity observed in the obese state. DESIGN: C57BL/6J wild...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Lee-Young, Robert S., Ayala, Julio E., Fueger, Patrick T., Mayes, Wesley H., Kang, Li, Wasserman, David H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049903/
https://ncbi.nlm.nih.gov/pubmed/21079619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2010.220
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