Obesity impairs skeletal muscle AMPK signaling during exercise: role of AMPKα2 in the regulation of exercise capacity in vivo

OBJECTIVE: Skeletal muscle AMP-activated protein kinase (AMPK)α2 activity is impaired in obese, insulin resistant individuals during exercise. We determined whether this defect contributes to the metabolic dysregulation and reduced exercise capacity observed in the obese state. DESIGN: C57BL/6J wild...

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Hlavní autoři: Lee-Young, Robert S., Ayala, Julio E., Fueger, Patrick T., Mayes, Wesley H., Kang, Li, Wasserman, David H.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049903/
https://ncbi.nlm.nih.gov/pubmed/21079619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ijo.2010.220
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